The Indianapolis Colts have done a pretty good job of keeping their focus through the first six games of the 2009 season.

Four road trips in three different time zones, ranging from one end of the country to the other, the Colts have been able to adjust and prosper. That’s why Indianapolis will take a 6-0 record into Sunday’s home game with the San Francisco 49ers.

“The thing that we try and do and have always done is that old cliche, ‘You really don’t get out ahead of yourself in terms of your focus and in terms of your preparation.’ You are just looking at one game. That’s it. We would like to just add them up at the end,” Colts coach Jim Caldwell said earlier this week.

“I do believe you don’t want to get to the point of looking out on the horizon and not focusing on what’s right there in front of you. For us, it’s the 49ers walking into our stadium on Sunday. We’d better be prepared to play.”

Caldwell knows the 49ers will be well-prepared to face Indianapolis this weekend.

“It’s very important that we focus in on a real good San Francisco team. They have a lot of weapons. They certainly have some firepower on offense with (running back Frank) Gore coming back. He’s a guy who can certainly run the ball. He will certainly be a factor in any ballgame. He can take it to the house at any point in time. He is a very capable runner. He also blocks well and can catch passes,” he said.

“There is obviously a little change in their quarterback situation. Looks like (Alex) Smith has done a tremendous job. He had three touchdown passes in the second half against Houston. He was very poised and under control. He threw the ball accurately. It’s going to be a real battle for us.”

Sanders ready to go again

Safety Bob Sanders came through last week’s game with the St. Louis Rams in pretty good shape.

Sanders made his first start of the season against the Rams and saw limited playing time (31 total plays). He had been sidelined since the start of training camp after undergoing knee surgery in the offseason.

“No swelling (in the knee). I just have to make sure that I continue to maintain and keep getting stronger,” Sanders said Thursday.

As for his overall performance in the St. Louis game, the former NFL Defensive Player of the Year proved to be his own worst critic.

“I’m always real critical of myself. I thought I played OK after the game, but when I go back and look at it, I feel like I missed some tackles. I left some plays out there that I should have made,” Sanders emphasized.

“Tackling should not be an issue for me, whether I haven’t played in a year or two years. It shouldn’t be an issue. It’s something that I’ve constantly worked on. I just have to make sure I get better.”